Xigduo XR 10/1000mg Tablet

Introduction

Xigduo XR 10/1000mg Tablet is a prescription oral medication used to help manage type 2 diabetes in adults. It combines two proven and complementary active ingredients: dapagliflozin (10mg) and metformin hydrochloride (1000mg). These work together to help lower blood sugar levels more effectively when diet and exercise alone are not enough. Dapagliflozin is part of the SGLT2 inhibitor class, while metformin is a biguanide, and both reduce the amount of sugar absorbed and produced by the body while supporting the kidneys in excreting excess glucose.

This dual-action formula helps improve glycemic control, may support weight management, and carries a lower risk of hypoglycemia compared to certain other diabetes medications. Xigduo XR is taken once daily in its extended-release form, offering steady, all-day blood sugar control. Commonly reported side effects include nausea, urinary tract infections, diarrhea, and headache. This medication is manufactured by AstraZeneca and sourced through certified channels at DoctorOnCall International, a licensed Malaysia-based online pharmacy verified for international patient safety.

General Indications

Xigduo XR 10/1000mg is used as an adjunct to diet and exercise to improve glycemic control in adults with type 2 diabetes mellitus. It is especially useful for individuals needing combination therapy that targets multiple pathways of glucose dysregulation. The extended-release formulation ensures smooth absorption to help prevent rapid fluctuations in blood sugar throughout the day.

Doctors commonly recommend Xigduo XR for patients with poorly controlled blood sugar who may want to avoid insulin therapy or who have intolerance to other medications. This medication is not intended for those with type 1 diabetes or diabetic ketoacidosis. International buyers choose DoctorOnCall International for its authentic medications, compliance with Malaysia’s Ministry of Health standards, multilingual support, and secure global delivery.

How to Take Xigduo XR 10/1000mg Tablet

Take Xigduo XR once daily with food, preferably in the morning, to reduce stomach discomfort. Swallow the tablet whole with a full glass of water. Do not chew, crush, or break the tablet, as this affects its extended-release mechanism. Taking it at the same time daily helps stabilize blood sugar levels.

If you miss a dose, take it when remembered unless it is near the next scheduled dose. Do not double doses. Avoid alcohol as it increases the risk of lactic acidosis. Always check with your doctor before combining Xigduo XR with any medications or supplements. Inform your doctor of long travels, fasting, or medical procedures that may require temporary adjustment of your treatment.

Dosage Information

Xigduo XR 10/1000mg is one of several strengths available. Your doctor will determine the right dose based on your medical history, kidney function, treatment response, and tolerance. Maximum recommended daily doses should not exceed 10mg of dapagliflozin and 2000mg of metformin. Other strengths such as 5/850mg, 5/1000mg, and 10/500mg may be used for dose titration.

Patients with renal impairment or older adults may need dosage adjustments. Do not adjust your dose without medical advice. All decisions regarding Xigduo XR should be guided by a qualified healthcare provider.

Shelf Life and Storage Instructions

The shelf life of Xigduo XR 10/1000mg is generally 24 to 36 months from the manufacturing date.

• Store at room temperature between 15°C and 30°C.
• Keep tablets in original blister packaging to protect from moisture.
• Avoid direct heat, sunlight, and humid environments.
• Store out of reach of children and pets.
• Carry medication in original packaging when traveling.
• Do not use beyond the expiry date.

Common Side Effects

• Nausea or upset stomach
• Diarrhea
• Urinary tract infections
• Headache
• Increased urination
• Genital yeast infections
• Loss of appetite

Seek medical attention if you experience severe abdominal pain, extreme tiredness, muscle pain, rapid breathing, or symptoms resembling a urinary tract infection.

Contraindications

• Type 1 diabetes or diabetic ketoacidosis
• Moderate to severe kidney disease or liver impairment
• Allergy to dapagliflozin, metformin, or inactive ingredients
• Pregnancy or breastfeeding unless advised by a doctor
• History of lactic acidosis from metformin use

Drug and Food Interactions

• Avoid excessive alcohol due to lactic acidosis risk.
• Use caution with diuretics, corticosteroids, or certain blood pressure medications.
• Inform your doctor if using insulin or sulfonylureas due to risk of hypoglycemia.
• Notify your doctor about all supplements and over-the-counter products.

Quick Tips

• Take Xigduo XR with meals.
• Stay hydrated, especially during physical activity or hot weather.
• Monitor your blood glucose regularly.
• Carry medical identification indicating your diabetes status.
• Do not stop taking the medication without consulting your doctor.
• Store tablets away from heat and moisture.
• Dispose of unused medication safely.

FAQs

All content and products on this website come from a fully licensed pharmacy and are carefully reviewed by qualified pharmacists to make sure they are safe, authentic, and reliable.