Comprimido Janumet XR 50/1000 mg

Introducción

Janumet XR 50/1000mg Tablet is an extended-release oral medication for managing Type 2 diabetes mellitus in adults. It combines sitagliptin (50mg) and metformin hydrochloride (1000mg) to control blood glucose by improving insulin response and reducing sugar production in the liver. Sitagliptin is a DPP-4 inhibitor that increases insulin after meals and lowers glucagon, while metformin improves how your body handles sugar.

When used alongside diet and exercise, Janumet XR helps reduce complications from uncontrolled blood sugar. Many patients report improved HbA1c levels over time. It is usually well-tolerated, with mild gastrointestinal issues, headache, or upper respiratory tract symptoms being the most common side effects. DoctorOnCall International ensures all Janumet XR tablets are authentic, Malaysia-licensed, and dispensed with professional support.

Indicaciones generales

Janumet XR 50/1000mg is prescribed for adults with Type 2 diabetes not adequately controlled by metformin or sitagliptin alone, or for those already taking both separately. It supports fasting and postprandial blood sugar control, helping reduce long-term complications such as neuropathy, retinopathy, heart disease, and kidney damage.

Its once-daily dosing improves adherence and convenience. Patients across Asia, Europe, the Middle East, and Africa trust licensed Malaysian pharmacies like DoctorOnCall International for authentic, timely, and safely delivered diabetes medications.

How to Take Janumet XR

Take Janumet XR once daily with food, preferably during the evening meal. Swallow the tablet whole—do not crush, cut, or chew. Maintain consistent timing for stable blood levels. Follow your doctor’s schedule, especially if combined with insulin or sulfonylureas. If a dose is missed, take it as soon as possible unless near the next dose. Stay hydrated, monitor symptoms, avoid alcohol, and maintain a healthy lifestyle to enhance effectiveness.

Información de dosificación

Each tablet contains sitagliptin 50mg and metformin 1000mg, taken once daily. Dosage may be adjusted based on kidney function, blood sugar, and tolerance. Alternate strengths (Janumet XR 50/500mg or 100/1000mg) may be prescribed. Do not self-adjust your dose. Monitoring of kidney function, blood sugar, and vitamin B12 levels is recommended for long-term treatment. Elderly patients or those with kidney issues may require tailored dosing.

Instrucciones de almacenamiento y vida útil

Janumet XR typically has a shelf life of 24–36 months. Check the expiry date before use.

• Store below 30°C (86°F) in a cool, dry place.
• Avoid direct sunlight, moisture, and heat sources.
• Do not store in bathrooms or near sinks.
• Keep in original packaging until use.
• Mantener fuera del alcance de los niños y las mascotas.
• For travel, pack in carry-on luggage with documentation.
• Discard broken or discoloured tablets safely.

Efectos secundarios comunes

• Náuseas o malestar estomacal
• Diarrea
• Dolor de cabeza
• Upper respiratory tract infection
• Sabor metálico en la boca
• Fatigue or dizziness

Seek immediate medical attention if you experience lactic acidosis symptoms, severe allergic reactions, or persistent vomiting.

Contraindicaciones

Do not take Janumet XR if you:

• Have Type 1 diabetes or diabetic ketoacidosis
• Have severely impaired kidney function or end-stage renal disease
• Are allergic to sitagliptin, metformin, or any ingredients
• Are pregnant, planning pregnancy, or breastfeeding (consult doctor)
• Have a history of lactic acidosis or related conditions

Interacciones entre medicamentos y alimentos

Use caution with:

• Alcohol (risk of lactic acidosis)
• Contrast dyes for imaging tests
• Diuretics, steroids, beta-blockers
• Cimetidine or other kidney-affecting drugs
• Other anti-diabetic medications (risk of low blood sugar)
• Large amounts of grapefruit juice (rare)

Always inform your doctor about all medications, supplements, and herbal products.

Consejos rápidos

• Take with food to reduce stomach upset.
• Stay hydrated and follow a balanced diet.
• Do not skip or double doses.
• Monitor blood sugar regularly.
• Attend scheduled lab check-ups.
• Report any new symptoms to your doctor.
• Avoid alcohol.
• Carry a diabetes ID when traveling internationally.

Preguntas frecuentes (FAQ)

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