Descripción
Introducción
Glucophage XR 500mg Tablet is a medically proven extended-release formulation of metformin hydrochloride, primarily prescribed to help manage blood sugar levels in individuals with type 2 diabetes mellitus. It works by reducing glucose production in the liver, improving insulin sensitivity, and enhancing peripheral glucose uptake. The extended-release (XR) version allows for once-daily dosing, offering better gastrointestinal tolerance and consistent blood sugar control over 24 hours. Glucophage XR does not cause weight gain and generally has a low risk of hypoglycemia when used alone.
This medication is widely used globally and is considered a frontline treatment for type 2 diabetes, either alone or with other diabetes medications. Proper use and clinical monitoring may improve HbA1c levels, stabilize blood sugar, and reduce long-term complication risks such as neuropathy, retinopathy, and cardiovascular issues. Mild side effects may include nausea, diarrhea, bloating, or metallic taste, while serious reactions are rare.
Indicaciones generales
Glucophage XR 500mg is indicated for adults and adolescents (10 years and above) diagnosed with type 2 diabetes mellitus, especially when diet and exercise alone are insufficient. It can be used as monotherapy or in combination with other antidiabetic drugs such as sulfonylureas or insulin. Off-label use may include polycystic ovary syndrome (PCOS) under expert supervision.
Its efficacy, affordability, and safety make Glucophage XR one of the most prescribed diabetes medications worldwide. Many international customers purchase it from DoctorOnCall International, a licensed Malaysian digital pharmacy ensuring authentic products, secure packaging, and regulatory compliance.
How to Take Glucophage XR 500mg
Take Glucophage XR exactly as prescribed. Usually, it is taken once daily with or after the evening meal to minimize stomach upset. Swallow the tablet whole with a full glass of water; do not crush or chew. Take at the same time each day for consistent blood sugar control.
If a dose is missed, take it as soon as possible unless near the next scheduled dose; do not double up. Persistent stomach upset may require adjustment in timing or a slower dose increase. Regular monitoring of blood sugar and kidney function is important, alongside adherence to dietary and lifestyle advice from your healthcare provider.
Información de dosificación
Glucophage XR 500mg is the typical starting dose for extended-release metformin therapy. Dose adjustments may occur gradually based on response, usually after 10–15 days. Maintenance doses often range between 1000 mg to 2000 mg per day, taken once or split into two doses with meals. Maximum daily dose should not exceed 2000 mg for most adults. Children and adolescents (10–17 years) should begin with 500 mg once daily under medical supervision. Always follow your doctor’s instructions; do not self-adjust.
Shelf Life and Storage Instructions
- Shelf life: 24–36 months from manufacture
- Store below 30°C (86°F) in a cool, dry place
- Keep tablets in original blister strip to protect from light, air, and moisture
- Avoid storing in bathrooms or humid environments
- Mantener fuera del alcance de los niños y las mascotas.
- Protect from direct sunlight and freezing, especially during travel
- For international shipping, ensure secure packaging and temperature protection
Efectos secundarios comunes
- Nausea or stomach discomfort
- Diarrea o heces blandas
- Sabor metálico en la boca
- Bloating or flatulence
Seek medical attention if severe abdominal pain, unusual tiredness, rapid breathing, or signs of lactic acidosis occur.
Contraindicaciones
Do not take Glucophage XR if you:
- Have severe kidney disease (eGFR <30 mL/min/1.73 m²)
- Have liver impairment or a history of lactic acidosis
- Are allergic to metformin or any tablet ingredients
- Are undergoing imaging with contrast dye (may require temporary suspension)
- Are pregnant or breastfeeding, unless instructed by a doctor
Consult your doctor before starting if you have other chronic conditions.
Interacciones entre medicamentos y alimentos
- Excessive alcohol may increase lactic acidosis risk
- Diuretics and ACE inhibitors may affect kidney function
- Contrast agents may require temporary discontinuation
- Some antacids containing magnesium can affect absorption
- High-carb or sugary diets may reduce effectiveness
Inform your doctor or pharmacist of all other medications or supplements being taken.
Consejos rápidos
- Take with food to reduce gastrointestinal side effects
- Check blood sugar regularly
- Stay hydrated
- Inform healthcare professionals before surgery or X-ray procedures with contrast
- Use consistently; do not stop without medical advice
Preguntas frecuentes (FAQ)
Q: Does DoctorOnCall International deliver Glucophage XR 500mg outside Malaysia?
A: Yes. International shipping is available to many countries, with delivery times depending on location.
Q: Is this product authentic and safe?
A: Yes. All medications are sourced from licensed Malaysian pharmacies and comply with strict regulatory standards.
Q: Do I need a prescription to order Glucophage XR internationally?
A: Yes. A valid prescription from a qualified healthcare provider is required.
Q: How should I store it while traveling internationally?
A: Keep tablets in original blister packs inside a dry, cool travel container. Avoid heat, moisture, and direct sunlight.
Q: Can children use Glucophage XR?
A: Children aged 10 and above with type 2 diabetes may use Glucophage XR, but only under pediatric medical supervision.
Q: Is Glucophage XR the same as regular Metformin?
A: It contains the same active ingredient but releases it more slowly, requiring fewer doses and improving tolerability for some users.
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